Recognising and investigating patients with ‘peculiar’ cases of diabetes is crucial for effective management. Five clinical vignettes explore complex scenarios in diabetes care, including latent autoimmune diabetes of adulthood, young-onset type 2 diabetes, post-transplant diabetes mellitus, euglycaemic diabetic ketoacidosis and pancreatic cancer risk with glucagon-like peptide-1 therapy.
- The clinical presentation of diabetes is diverse and certain clinical features can help identify patients who require more detailed assessment.
- Reaching a specific diabetes diagnosis and understanding the underlying pathophysiology is important for optimal management.
- Most people with diabetes are managed in primary care, although those with complex cases of diabetes often benefit from the involvement of a multidisciplinary team, including an endocrinologist.
- As therapeutics in diabetes are rapidly advancing, clinicians need to be vigilant for potential adverse effects and provide appropriate education to patients.